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. 2016 Sep 16;10(10):1516–1531. doi: 10.1016/j.molonc.2016.08.005

Figure 6.

Figure 6

MiR‐155 is deregulated in metastatic chemoresistant lung tissues. (A–B) Relative expression of miR‐155 in metastatic lung cancer tissues in comparison with chemonaive non‐metastatic tissues. (B) miR‐155 expression was significantly lower in patients with advanced pathological stage (III–IV) and lymph node metastasis. (C) LC‐DR cells were treated with autophagy inhibitor chloroquine (20 μΜ) or carboplatin (25 μΜ) for 24 h and miR‐155 expression was evaluated. (D) Effect of miR‐155 transfected LC‐DR cells in TILs expression. MiR‐155 expression was normalized to U6 expression. Data represent the mean ± SD of three independent experiments (*P < 0.05; **P < 0.01).