Table 1.
Differentially expressed snoRNAs (Metastatic vs. Non‐Metastatic PCa xenograft). RMS, root mean square. RPKM, reads per kilobase of transcript per million mapped reads. We report transcripts with RMS‐normalized RPKM ratio>2 or <0.5 (Metastatic vs. Non‐Metastatic xenograft, RNA Seq. data). Transcripts up‐regulated in the metastatic xenograft are in red, transcripts down‐regulated in the metastatic xenograft are in blue. Transcripts up‐regulated in the metastatic xenograft are ranked based on absolute expression level in LTL313H cells. Transcripts down‐regulated in the non‐metastatic xenograft are ranked based on absolute expression in LTL313B cells.
| Gene name | Met. | Non‐met. | RMS‐normalized RPKM ratio | Represented in MSKCC database? |
|---|---|---|---|---|
| SNORA6 | 52.24 | 17.85 | 3.383431953 | Yes |
| SNORA42 | 28.86 | 10.59 | 3.153692615 | Yes |
| SNORA62 | 25.9 | 12.75 | 2.349627175 | Yes |
| SNORD88A | 13.78 | 6.397 | 2.491743725 | No |
| SNORA55 | 10.8 | 3.559 | 3.511427723 | Yes |
| SCARNA20 | 8.448 | 3.751 | 2.605070423 | No |
| SNORA11B | 8.337 | 3.166 | 3.045045045 | No |
| SNORA18 | 5.064 | 0.6716 | 8.721094856 | Yes |
| SNORA45 | 4.374 | 1.692 | 2.990630856 | Yes |
| SNORA72 | 1.809 | 0.3358 | 6.228373702 | Yes |
| SNORA26 | 1.174 | 0.3633 | 3.736551323 | No |
| SNORD33 | 1.151 | 0.534 | 2.490603363 | Yes |
| SNORA22 | 1.077 | 0.3333 | 3.736925515 | Yes |
| SNORD88B | 0.9845 | 0.457 | 2.492485549 | No |
| SCARNA18 | 0.7235 | 0.3358 | 2.491349481 | No |
| SNORA64 | 233.5 | 70.91 | 0.351062867 | Yes |
| SNORA63 | 32.83 | 13.09 | 0.461068211 | No |
| SNORA81 | 13.94 | 4.829 | 0.400454545 | No |
| SNORA31 | 4.432 | 1.102 | 0.287416587 | Yes |
| SNORA51 | 4.365 | 1.447 | 0.383349468 | Yes |
| SNORA76 | 2.015 | 0.7235 | 0.415312008 | No |