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. 2016 Aug 17;10(9):1450–1460. doi: 10.1016/j.molonc.2016.08.003

Figure 1.

Figure 1

Patient disease courses and patient samples analysed. (A) Biopsy sites in the three selected patients. (B) Sample and treatment timeline. Samples procured for whole exome sequencing are indicated in green below each timeline. Patient 1: 8× Tumour Regions, 1× Lymph Node Bulk. Patient 2: 3× Tumour Regions, 1× Lymph Node Pool, 2× Distant Metastasis Regions. Patient 3: 3× Tumour Regions, 2× Lymph Node Regions, 2× Distant Metastasis Regions. Bulk: DNA extracted from 5 to 10 cross sections of the biopsy, Reg.: DNA extracted from cellular regions procured by LMD or puncture, Pool: pool of exomes performed on cellular regions A–C.