Table 4.
Size, zeta potential and PDI of nanoparticles with optimum preparation parameters
| Formulation |
Z
ave
(nm)
**
(mean±SD) |
Size (nm)
(TEM) |
PDI
*
(mean±SD) |
Zeta potential (mV)
(mean±SD) |
|---|---|---|---|---|
| SPION | 2.2±20.1 | 7.0±0.5 | 0.20±0.05 | +20.2±2.0 |
| PLGA | 190.6±8.6 | - | 0.03±0.01 | -15.3±0.5 |
| SPION- PLGA | 170.3±4.6 | - | 0.16±0.04 | -12.1±1.0 |
| PLGA-Gem | 175.2±8.3 | - | 0.05±0.02 | -14.2±1.1 |
| SPION-PLGA-Gem | 180.2±10.3 | 180.0±20.0 | 0.08±0.02 | -13.3±1.0 |
*
Poly Disperse Index (PDI), Zave and zeta potential (mV) were obtained by DLS.