Table 4.

Increase in BMD following two years of using transdermal estrogen

Study	Effect size (95% confidence interval)	% weight
Kim (25)	0.038 (0.006 – 0.193)	7.01
Ettinger(27)	0.041 (0.020 – 0.082)	45.12
Adami(31)	0.005 (0.001 – 0.285)	19.09
Alexandersen(32)	0.048 (0.019 – 0.0114)	20.19
Gonnelli(33)	0.057 (0.018 – 0.165)	8.60
Fixed pooled	0.037 (0.017 – 0.057)	100