. 2017 Mar 31;8(1):e5. doi: 10.5037/jomr.2017.8105

Table 1.

Predictors of lymphoma development in Sjögren’s syndrome

Clinical	Serological
Persistent parotid gland enlargement	Mixed monoclonal cryoglobulinemia

Splenomegaly	Low serum C4 levels

Lymphadenopathy	Serum or urine monoclonal bands

Palpable purpura	CD4 + T lymphocytopenia^a

Leg ulcers	Neutropenia^a

Peripheral neuropathy	High serum β2 microglobulin^a

Previous low-dose irradiation or chemotherapy	Low serum IgM levels^a

	Disappearance of previously positive rheumatoid factor

^aΙndicates detected findings in the present case.