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. Author manuscript; available in PMC: 2018 Mar 14.
Published in final edited form as: Circulation. 2016 Dec 27;135(11):1011–1020. doi: 10.1161/CIRCULATIONAHA.116.024421

Figure 1. Expression of plasminogen activators and plasminogen at the site of pulmonary emboli.

Figure 1

Lung tissue containing FITC-fibrin labeled (green) pulmonary emboli was immunostained (red) to detect the expression of (A) tPA, (B) uPA and (C) plasminogen (Pg) (D) The total immune-stained area (arbitrary units; a.u) for each protein was measured in a 20× (100 μm) image of an embolized vs non embolized (Control; dashed yellow outline) pulmonary artery in the lungs. n=3, mean ± SEM. **p<0.01; ns, non-significant.