Table 3.
Microarray analysis of the expression of genes isolated from Acinetobacter baumanni isogenic strains cultured in the presence (0.5%) and absence of bile salts.
| Gene name | Protein Description | Fold | Function |
|---|---|---|---|
| Acinetobacter baumannii ATCC 17978 vs. Acinetobacter baumannii ATCC 17978 (0.5 % Bile Salts) | |||
| A1S_3175 | Bacterioferritin | 5.21 | Ferric iron binding |
| A1S_0800 | Bacterioferritin | 2.71 | |
| A1S_1860 | Ring hydroxylating dioxygenase Rieske (2Fe-2S) protein | 2.27 | Iron/Sulfur metabolism |
| A1S_1859 | Aromatic-ring-hydroxylating dioxygenase beta subunit | 2.21 | |
| A1S_2102 | Aldehyde dehydrogenase 1 | 3.57 | Oxidoreductase activity |
| A1S_1864 | Acyl-CoA dehydrogenase-like protein | 2.34 | |
| A1S_1858 | Short-chain dehydrogenase/reductase SDR | 2.17 | |
| A1S_1865 | Glu-tRNA amidotransferase | 2.66 | Transferase activity |
| A1S_3415 | Maleylacetoacetate isomerase | 2.5 | Isomerase activity |
| A1S_1857 | Vanillate O-demethylase oxidoreductase | 2.31 | Catalytic activity |
| A1S_3414 | Fumarylacetoacetase | 2.14 | Fumarylacetoacetate activity |
| A1S_2809 | Bacteriolytic lipoprotein entericidin B | 2.03 | Response to toxic substance |
| A1S_1228 | Cold shock protein | 2 | DNA binding |
| A1S_1924 | Cytochrome d terminal oxidase polypeptide subunit I | 2.34 | Component of membrane |
| Acinetobacter baumannii ATCC 17978ΔadeB vs. Acinetobacter baumannii ATCC 17978ΔadeB (0.5% Bile Salts) | |||
| A1S_3175 | Bacterioferritin | 4.17 | Ferric iron binding |
| A1S_0800 | Bacterioferritin | 3.64 | |
| A1S_1860 | Ring hydroxylating dioxygenase Rieske (2Fe-2S) protein | 2.79 | Iron/Sulfur Metabolism |
| A1S_1859 | Aromatic-ring-hydroxylating dioxygenase beta subunit | 2.73 | |
| A1S_1861 | Benzoate dioxygenase large subunit | 2.43 | |
| A1S_2102 | Aldehyde dehydrogenase 1 | 2.39 | Oxidoreductase activity |
| A1S_1864 | Acyl-CoA dehydrogenase-like protein | 2.79 | |
| A1S_1858 | Short-chain dehydrogenase/reductase SDR | 2.53 | |
| A1S_1075 | D-amino-acid dehydrogenase | 2.62 | |
| A1S_1856 | P-hydroxyphenylacetate hydroxylase C1:reductase component | 2.01 | |
| A1S_1865 | Glu-tRNA amidotransferase | 2.97 | Transferase activity |
| A1S_3415 | Maleylacetoacetate isomerase | 2.59 | Isomerase activity |
| A1S_1857 | Vanillate O-demethylase oxidoreductase | 2.47 | Catalytic activity |
| A1S_3414 | Fumarylacetoacetase | 2.12 | Fumarylacetoacetate activity |
| A1S_0804 | Trehalose-6-phosphate phosphatase | 3.66 | Metal ion binding |
| A1S_1498 | TetR family transcriptional regulator | 2.28 | Transcriptional regulator |
| A1S_1687 | Transcriptional regulator | ||
| A1S_3416 | Glyoxalase/bleomycin resistance protein/dioxygenase | 2.11 | Dioxygenase activity |
| A1S_1773 | RND family drug transporter | 2.04 | Integral component membrane |
| A1S_1228 | Cold shock protein | 4.27 | DNA binding |
| Acinetobacter baumanniiATCC 17978ΔadeL vs. Acinetobacter baumannii ATCC 17978ΔadeL Bile Salts (0.5% Bile Salts) | |||
| A1S_3175 | Bacterioferritin | 7.63 | Ferric iron binding |
| A1S_0800 | Bacterioferritin | 5.5 | |
| A1S_2102 | Aldehyde dehydrogenase 1 | 2.59 | Oxidoreductase activity |
| A1S_1865 | Glu-tRNA amidotransferase | 2.26 | Transferase activity |
| A1S_3415 | Maleylacetoacetate isomerase | 3.9 | Isomerase activity |
| A1S_3317 | Putative outer membrane protein | 2.68 | Component of membrane |
| A1S_3414 | Fumarylacetoacetase | 2.89 | Fumarylacetoacetate activity |
| A1S_2809 | Bacteriolytic lipoprotein entericidin B | 2.76 | Response to toxic substance |
| A1S_1687 | Transcriptional regulator | 2.68 | Transcriptional regulator |
| A1S_3416 | Glyoxalase/bleomycin resistance protein/dioxygenase | 3.17 | Dioxygenase activity |
| A1S_1962 | Recombinase A | 2.84 | DNA metabolism |
| A1S_1224 | Curved DNA-binding protein | 2.16 | |
| A1S_1228 | Cold shock protein | 4.92 | |
| A1S_1031 | DNA-binding ATP-dependent protease La | 2.75 | ATP binding |
| A1S_1030 | DNA-binding ATP-dependent protease La | 2.26 | |
| A1S_1950 | Putative universal stress protein | 2.36 | Response to stress |
| A1S_0364 | Transposase | 2.18 | Mobility of genes |
| A1S_0683 | Putative sigma (54) modulation protein RpoX | 2.12 | General metabolism |
| A1S_1987 | Putative UDP-galactose 4-epimerase (GalE-like) | 2.12 | |