Figure 3.

DCA. DCAs depict the clinical net benefit in pairwise comparisons between integrated nomogram, BCLC stage, and CLIP score. Nomograms are compared against the BCLC stage and CLIP score in terms of 2‐ and 3‐year OS (A, B) and 2‐ and 3‐year RFS (C, D). Dashed lines indicate the net benefit of nomogram in each of the curves across a range of threshold probabilities. The horizontal solid black line represents the assumption that no patients will experience the event, and the solid gray line represents the assumption that all patients will die or relapse. On DCA, nomogram showed superior net benefit compared to BCLC stage and CLIP score across a range of threshold probabilities.

Abbreviations: BCLC, Barcelona Clinic Liver Cancer; CLIP, Cancer of the Liver Italian Program; DCA, decision curve analysis; RFS, recurrence‐free survival; OS, overall survival.