Table 3.
Comparison of orthopedic infections due to Pseudomonas spp versus other pathogens.
| Other than Pseudomonas | Pseudomonas spp | ||
|---|---|---|---|
| n=1697 (92%) | p value | n=194 (8%) | |
| Patient characteristics | |||
| F:M (percentage of female) | 596:1101 (35%) | ns | 56:87 (39%) |
| Median age | 56 years | ns | 56 years |
| - Age < 51 | 705 (42%) | 60 (42%) | |
| - Age 51 to 80 | 795 (47%) | 69 (51%) | |
| - Age > 80 | 197 (12%) | 14 (10%) | |
| Median serum C-reactive protein level | 87 mg/L | <0.01 | 66 mg/L |
| - CRP < 51mg/L | 490 (29%) | 45 (31%) | |
| - CRP 51 to 200mg/L | 527 (31%) | 44 (31%) | |
| - CRP > 200mg/L | 680 (40%) | 54 (38%) | |
| Prior antibiotic use | 712 (42%) | <0.01 | 78 (55%) |
| Median duration of prior antibiotic use | 4 days | ns | 5 days |
| Immune-compromised+ | 556 (33%) | ns | 42 (29%) |
| - Diabetes mellitus | 306 (18%) | ns | 25 (17%) |
| Type of infection | |||
| Osteoarticular infections | 952 (56%) | ns | 71 (50%) |
| All implant-associated infections | 588 (35%) | ns | 46 (32%) |
| - Prosthetic joint infections | 308 (18%) | <0.01 | 13 (9%) |
| - Spondylodesis infections | 25 (1%) | 0.02 | 6 (4%) |
| - Nail infections | 49 (3%) | ns | 4 (3%) |
| - Plate infections | 123 (7%) | ns | 12 (8%) |
| Soft tissue abscess | 472 (28%) | 0.01 | 26 (18%) |
| Shoulder infections | 91 (5%) | 0.01 | 1 (1%) |
| Spine infections | 74 (4%) | ns | 3 (2%) |
| Polymicrobial infections | 324 (22%) | <0.01 | 71 (50%) |
ns = not significant
+ = diabetes, immune-suppressive medication, dialysis, active cancer, untreated HIV disease, cirrhosis CHILD C, pregnancy, splenectomy.