Table 1. Laboratory assessment of HIV-infected patients with cryptococcal meningitis.
| Parameters | Baseline N = 33 | Week 2 N = 23 | Week 10 N = 16 | Week 16 N = 15 | |
|---|---|---|---|---|---|
| CD4+ T-cell count, cells/μL | 37 (19–81) | NA | NA | 89 (79–152) | |
| HIV load, log10 copies RNA/mL | 5.2 (4.5–6.1) | NA | NA | 1.8 (1.2–3.1) | |
| CSF log10 CFU/mL | 5.32 (3.76–5.9) | 1.07 (0–2.1) | negative | negative | |
| CSF CrAg titer | 1024 (512–4096) | 256 (128–512) | 128 (32–128) | 32 (8–64) | |
| CSF WBC count, cells/μL | 15 (1–114) | 21 (10–118) | 28 (14–139) | 35 (19–157) | |
| CSF glucose, mg/dL | 27.9 (19–51.2) | 37.4 (22.5–54) | 49.3 (35.1–58.2) | 54.1 (38.9–73.6) | |
| CSF protein, g/dL | 0.78 (0.42–1.5) | 0.69 (0.39–1.1) | 0.56 (0.38–0.93) | 0.43 (0.34–0.73) | |
The data presented are medians (interquartile range, [IQR]). Abbreviations: CFU, Colony-forming units; CrAg, cryptococcal glucuronoxylomannan antigen; CSF, cerebrospinal fluid; WBC, white blood cell; NA, not available.