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. 2017 May 9;12(5):e0177224. doi: 10.1371/journal.pone.0177224

Fig 6. Quantification of histone acetylation level in rcd1, xlpra2, erd and xlpra1 retinas.

Fig 6

Quantification of histone acetylation on western blots (Fig 2B) normalized against the corresponding housekeeping protein (ACTB) was done using Li-COR Odyssey Fc and represented as fold-changes compared to the normal tissue values. Differences in relative fluorescence (Y-axis) for the proteins analyzed (X-axis) show 14 KDa-Acetyl-Lysine levels decrease in rcd1 and xlpra2 at 7 wks but remain the same as normal in all other samples. 17 KDa-Acetyl-Lysine was increased in all samples except in 7 wks rcd1 (decreased) and 16 wks rcd1 (same as normal). In contrast, acetylated H3 histone shows mostly unchanged pattern, except in 16 wks xlpra2 where it was increased. * indicates significance level 5% (p<0.05).