Table 2. Comparative analysis of differentially expressed genes in study models: Neuroprotective and anti-inflammatory group.
DE genes between rcd1, xlpra2, erd and xlpra1 mutants compared to normal at different ages.
| DE genes | FC rcd1 vs. normal | FC xlpra2 vs. normal | FC erd vs. normal | FC xlpra1 vs. normal |
|---|---|---|---|---|
| 5 wks | 5 wks | |||
| LIF | 6.1 | n.s. | ||
| 7 wks | 7 wks | |||
| CX3CR1 | 2.1 | n.s. | ||
| LIF | 29.1 | 5.0 | ||
| IL4 | 2.4 | n.s. | ||
| EGF | 2.6 | n.s. | ||
| EGFR | 3.4 | n.s. | ||
| 16 wks | 16 wks | 9.6–12 wks | 16 wks | |
| IL1RN | 20.6 | 10.8 | 2.0 | n.s. |
| CX3CL1 | 2.9 | n.s. | n.s. | n.s. |
| CX3CR1 | 11.4 | 4.2 | n.s. | n.s. |
| PDGFA | 2.4 | n.s. | 4.9 | n.s. |
| PDGFRB | 3.8 | n.s. | 2.0 | -2.1 |
| LIF | 8.7 | 17.4 | n.s. | 3.0 |
| TGFB1 | 3.7 | 4.5 | 2.8 | n.s. |
| IL4 | 2.1 | n.s. | n.s. | 14.9 |
| EGF | 2.8 | n.s. | n.s. | n.s. |
| EGFR | 9.0 | 2.6 | n.s. | n.s. |
| FGFR1 | 6.1 | n.s. | n.s. | n.s. |
| FGF2 | 3.9 |