Table 2.
Correlations of abdominal and femoral subcutaneous adipose tissue estrogen receptor alpha (ESR1) and estrogen receptor beta (ESR2) mRNA expression with age, fat mass, serum estradiol and leptin among pre-and postmenopausal women.
ESR1 | ESR2 | ESR1:ESR2 | |||||
---|---|---|---|---|---|---|---|
Abdominal | Femoral | Abdominal | Femoral | Abdominal | Femoral | ||
Pearson Correlations | |||||||
Age | −0.380* | −0.353* | 0.014 | 0.137 | −0.463** | −0.472** | |
%fat | −0.291† | −0.219† | −0.028 | −0.053 | −0.359* | −0.211† | |
Total fat mass | −0.178 | −0.160 | −0.139 | −0.061 | −0.127 | −0.156 | |
Trunk fat mass | −0.270† | −0.256† | −0.162 | −0.048 | −0.247† | −0.264† | |
Leg fat mass | −0.007 | −0.004 | −0.078 | −0.078 | 0.082 | −0.029 | |
VFA | −0.233† | −0.248† | −0.129 | −0.055 | −0.224 | −0.229† | |
Abdominal SFA | −0.155 | −0.179 | −0.038 | −0.032 | −0.296† | −0.250† | |
Femoral SFA | 0.022 | 0.030 | 0.130 | −0.038 | −0.071 | 0.042 | |
Serum E2 | 0.155 | 0.148 | −0.011 | −0.123 | 0.258† | 0.496** | |
Serum Leptin | −0.248† | −0.294* | −0.215 | −0.082 | −0.130 | −0.218† | |
Partial Correlations | |||||||
Age (adjusted for %fat) | −0.336* | −0.320* | −0.021 | 0.152 | −0.417** | −0.446** | |
Age (adjusted for E2) | −0.361* | −0.327* | 0.010 | 0.085 | −0.398* | −0.285+ | |
Age (adjusted for leptin) | −0.417** | −0.405** | −0.005 | 0.129 | −0.480** | −0.511** |
p≤0.05;
p≤0.01;
p≤0.15;
VFA = visceral fat area; SFA = subcutaneous fat area; E2 = estradiol.