Table 1.
No. of participants | 31 | |
Age at onset, years | 62.5 (6.8) | Range: 53–76 |
Age at enrollment, years | 67.2 (6.9) | Range: 56–83 |
Gender | Male: 13 | Female: 18 |
Handedness | Right: 30 | Left: 1 |
Education, years | 16.1 (2.4) | |
Symptom duration, years | 4.3 (2.2) | |
Clinical diagnosis |
PPA: 28 |
Other dementia diagnosis: 3 |
Initial evaluation |
6-Month evaluation |
|
WAB-R-AQ (%) | 81.3 (13.9)* | 76.7 (17.5) |
MMSE (out of 30) | 24.1 (5.0) | 23.7 (5.5) |
BNT (%) | 60.9 (29.5)∗ | 54.7 (31.0) |
Abbreviations: BNT, Boston Naming Test; MMSE, Mini-Mental State Examination; PPA, primary progressive aphasia; WAB-R-AQ, Western Aphasia Battery Revised.
NOTE. Numbers are provided as means (standard deviations [italicized]). Other dementia diagnosis consisted of one person with prominent apraxia of speech, one with apathy and aphasia, and one with aphasia, working memory, and processing speed deficits. Clinician-rated aphasia severity is based on the initial evaluation. All participants were fluent in English. English was the native language for 29 of the participants. Spanish and Arabic were the native languages for the other two participants. The aphasia quotient from the WAB-R-AQ was used as a global measure of aphasia severity [31]. The BNT was used to assess the naming of objects [32]. Because of participant language deficits, a modified multiple-choice version of the MMSE [33] was used for 12 individuals at the initial evaluation and 20 individuals at the 6-month evaluation.
Pairwise t tests indicated significant decline (P < .05).