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Three hundred micromoles of urea were injected (ip) just after the first 2-h urine collection (time 0). A. urinary osmolality (Uosm). B. urinary output. C. urinary urea concentration (Uurea). D. urea excretion (excr.). E. nonurea solute concentration (Unon-urea solutes). F. excretion of non-urea solutes. Data are presented as means ± SEM. n = 6. *p < 0.05 vs. wild-type mice.
