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. 2017 Apr 8;6:e25754. doi: 10.7554/eLife.25754

Video 1. Conformational changes in VAT upon substrate binding.

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DOI: 10.7554/eLife.25754.011

Interpolation between the stacked-ring and substrate-bound states of VAT, shown as ribbon diagrams (left) and Cα positions for the pore loop residues (right). The complex is viewed ~15° from the symmetry axis so that in the substrate-bound state the complex is viewed along the substrate path. Substrate is shown in red. Scale bars 25 Å. Please view video as loop.

DOI: http://dx.doi.org/10.7554/eLife.25754.011