Table 3.
Risk of Hospitalization, Stroke, and Death with Atrial Fibrillation in Patients with Prior Heart Failure Hospitalization (N=2,449)
Outcome | Events | Incidence rate per 100 person-years | Model 1* HR (95%CI) | P-value | Model 2† HR (95%CI) | P-value | P-interaction for Gender |
---|---|---|---|---|---|---|---|
Hospitalization | 1,082 | 17.8 (16.8, 18.9) | 1.69 (1.49, 1.91) | <0.001 | 1.57 (1.38, 1.78) | <0.001 | 0.22 |
Hospitalization for Heart Failure | 313 | 3.9 (3.5, 4.4) | 1.86 (1.48, 2.34) | <0.001 | 1.65 (1.31, 2.09) | <0.001 | 0.73 |
Stroke | 83 | 1.0 (0.8, 1.2) | 2.21 (1.42, 3.44) | <0.001 | 2.31 (1.46, 3.68) | <0.001 | 0.30 |
Death | 365 | 4.3 (3.9, 4.7) | 1.40 (1.13, 1.72) | 0.0019 | 1.29 (1.04, 1.61) | 0.022 | 0.72 |
Cardiovascular Death | 244 | 2.9 (2.5, 3.3) | 1.51 (1.17, 1.95) | 0.0018 | 1.42 (1.09, 1.86) | 0.0096 | 0.87 |
Adjusted for age, race, and gender.
Adjusted for Model 1 covariates plus smoking, systolic blood pressure, diabetes, body mass index, angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers, beta blockers, statin, randomization group, New York Heart Association functional classification, coronary heart disease, and stroke.
CI=confidence interval; HR=hazard ratio.