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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Clin Psychol Rev. 2016 Nov 9;64:41–56. doi: 10.1016/j.cpr.2016.11.003

Figure 2. Theorized postnatal development of selected aspects of the human reward system warranting further study.

Figure 2

Figure 2 is a schematic diagram depicting the theorized longitudinal developmental trajectories for selected white-matter tissue tracts, functional responses and aspects of dopaminergic development hypothesized to relate to initial responsiveness to reward attainment (RDoC) and to the development of childhood and adolescent addictive and impulsive disorders. Trajectories are based on data reported in (Casey, 2014; Galvan, et al., 2006; Giedd, 2004; Gogtay, et al., 2004; Lebel & Beaulieu, 2011; Lebel, et al., 2008; Raznahan, et al., 2014; Wahlstrom, et al., 2010b).

DLPFC = dorsolateral prefrontal cortex; OFC = orbitofrontal cortex; PFC = prefrontal cortex