Table 2.
Unadjusted and adjusted odds ratios (OR) with 95% confidence intervals (CI) for hyperemesis gravidarum (n = 611, 0.9%) among 69,864 pregnancies
| Unadjusted OR (95% CI) | P value | Adjusted OR (95% CI) | P value | |
|---|---|---|---|---|
| History of depression | ||||
| No | 1 | – | 1 | – |
| Yes | 1.53 (1.29; 1.83) | < 0.001 | 1.49 (1.23; 1.79) | <0.001 |
| Symptoms of current depression | ||||
| Low score | 1 | – | 1 | – |
| High score | 2.11 (1.65; 2.69) | < 0.001 | 1.71 (1.31; 2.23) | <0.001 |
| Maternal age | 0.94 (0.93; 0.96) | < 0.001 | 0.93 (0.91; 0.95) | <0.001 |
| Parity | ||||
| Primipara | 1 | – | 1 | – |
| Multipara | 1.24 (1.05; 1.45) | 0.010 | 1.43 (1.20; 1.69) | <0.001 |
| Length of education (years) | ||||
| <12 | 2.42 (1.76; 3.32) | < 0.001 | 1.91 (1.36; 2.69) | <0.001 |
| 13–16 | 1.64 (1.31; 2.06) | < 0.001 | 1.44 (1.13; 1.82) | 0.003 |
| >16 | 1 | – | 1 | – |
| Pre-pregnancy BMI | 1.03 (1.01; 1.04) | 0.002 | 1.02 (1.00; 1.04) | 0.030 |
| Smoking | ||||
| No | 1 | – | 1 | – |
| Yes | 0.60 (0.49; 0.72) | <0.001 | 0.46 (0.37; 0.56) | <0.001 |
| Sex of the child | ||||
| Boy | 1 | – | 1 | – |
| Girl | 1.49 (1.27; 1.75) | <0.001 | 1.50 (1.28; 1.76) | <0.001 |
| Pelvic girdle pain | ||||
| No | 1 | – | 1 | – |
| Yes | 1.52 (1.25; 1.85) | <0.001 | 1.30 (1.06; 1.59) | 0.011 |