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. 2017 Mar 1;73(6):735–742. doi: 10.1007/s00228-017-2218-2

Table 2.

Prescribing frequency and frequency of affected patients for each identified PIM

ATC code Drug class/name Prescriptions, n (col %) Patients, n (col %) 175
A02 Drugs for acid-related disorders 2 (0.9) 2 (1.1)
Aluminium-containing antacids (A02AD01) 1 (0.4) 1 (0.6)
Ranitidine (A02BA02) 1 (0.4) 1 (0.6)
A03F Drugs for functional gastrointestinal disorders—propulsives 3 (1.3) 3 (1.7)
Metoclopramide (A03FA01) 3 (1.3) 3 (1.7)
A06A Laxatives 19 (8.4) 19 (10.9)
Sodium picosulfate (A06AB08) 19 (8.4) 19 (10.9)
A10B Blood glucose-lowering drugs, excl. insulins 16 (7.1) 16 (9.1)
Glibenclamide (A10BB01) 8 (3.5) 8 (4.6)
Glimepiride (A10BB12) 1 (0.4) 1 (0.6)
Glipizide (A10BB07) 7 (3.1) 7 (4.0)
B01A Antithrombotic agents 6 (2.7) 6 (3.4)
Dabigatran (B01AE07) 2 (0.9) 2 (1.1)
Dipyridamole (B01AC07) 4 (1.8) 4 (2.3)
C01 Cardiac therapy 36 (15.9) 36 (20.1)
Digoxin (C01AA05) 33 (14.6) 33 (18.9)
Amiodarone (C01BD01) 2 (0.9) 2 (1.1)
Ivabradine (C01EB17) 1 (0.4) 1 (0.6)
C02 Antihypertensives 4 (1.8) 4 (2.3)
Doxazosin (C02CA04) 3 (1.3) 3 (1.7)
Hydralazine (C02DB02) 1 (0.4) 1 (0.6)
C03D Diuretics—potassium-sparing agent 5 (2.2) 5 (2.9)
Spironolactone (>25 mg/day) (C03DA01) 5 (2.2) 5 (2.9)
C07A Betablocking agents 3 (1.3) 3 (1.7)
Pindolol (C07AA03) 2 (0.9) 2 (1.1)
Propranolol (C07AA05) 1 (0.4) 1 (0.6)
C08 Calcium channel blockers 4 (1.8) 4 (2.3)
Nifedipine (C08CA05) 1 (0.4) 1 (0.6)
Diltiazem (C08DB01) 2 (0.9) 2 (1.1)
Verapamil (C08DA01) 1 (0.4) 1 (0.6)
G03C Oestrogens 6 (2.7) 6 (3.4)
Estriol (oral) (G03CA04) 6 (2.7) 6 (3.4)
G04B Other urologicals, incl. antispasmodics 12 (5.3) 12 (6.9)
Darifenacin (G04BD10) 1 (0.4) 1 (0.6)
Fesoterodin (G04BD11) 1 (0.4) 1 (0.6)
Solifenacin (G04BD08) 6 (2.7) 6 (3.4)
Tolterodine (G04BD07) 4 (1.8) 4 (2.3)
M01A Anti-inflammatory and antirheumatic products—NSAID (oral) 3 (1.3) 3 (1.7)
Diclofenac (M01AB05) 1 (0.4) 1 (0.6)
Ketoprofen (M01AE03) 2 (0.9) 2 (1.1)
M03B Muscle relaxants—centrally acting agents 1 (0.4) 1 (0.6)
Orphenadrine (M03BC01) 1 (0.4) 1 (0.6)
N02A Analgesics—opioids 4 (1.8) 4 (2.3)
Tramadol (N02AX02) 4 (1.8) 4 (2.3)
N03A Antiepileptics 10 (4.4) 10 (5.7)
Carbamazepine (N03AF01) 7 (3.1) 7 (4.0)
Clonazepam (N03AE01) 2 (0.9) 2 (1.1)
Phenytoin (N03AB02) 1 (0.4) 1 (0.6)
N04 Antiparkinson drugs 5 (2.2) 5 (2.9)
Pramipexole (N04BC05) 3 (1.3) 3 (1.7)
Trihexyphenidyl (N04AA01) 2 (0.9) 2 (1.1)
N05A Antipsychotics 7 (3.1) 7 (4.0)
Clozapine (N05AH02) 1 (0.4) 1 (0.6)
Haloperidol (>2 mg single dose; >5 mg/day) (N05AD01) 2 (0.9) 2 (1.1)
Lithium (N05AN01) 2 (0.9) 2 (1.1)
Perphenazine (N05AB03) 2 (0.9) 2 (1.1)
N05B Anxiolytics 5 (2.2) 5 (2.9)
Alprazolam (N05BA12) 5 (2.2) 5 (2.9)
N05C Hypnotics and sedatives 57 (25.2) 57 (32.6)
Clomethiazole (N05CM02) 3 (1.3) 3 (1.7)
Flunitrazepam (N05CD03) 2 (0.9) 2 (1.1)
Nitrazepam (N05CD02) 1 (0.4) 1 (0.6)
Propiomazine (N05CM06) 10 (4.4) 10 (5.7)
Triazolam (N05CD05) 1 (0.4) 1 (0.6)
Zolpideme (>5 mg/day) (N05CF02) 1 (0.4) 1 (0.6)
Zopiclone (>3.75 mg/day) (N05CF01) 39 (17.3) 39 (22.3)
N06A Antidepressants 15 (6.6) 15 (8.6)
Amitryptiline (N06AA09) 7 (3.1) 7 (4.0)
Bupropion (N06AX12) 1 (0.4) 1 (0.6)
Paroxetine (N06AB05) 2 (0.9) 2 (1.1)
Venlafaxine (N06AX16) 5 (2.2) 5 (2.9)
R03D Other systemic drugs for airway diseases 1 (0.4) 1 (0.6)
Theophylline (R03DA04) 1 (0.4) 1 (0.6)
R06A Antihistamines for systemic use 2 (0.9) 2 (1.1)
Clemastine (R06AA04) 2 (0.9) 2 (1.1)