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. 2017 Mar 14;8:14689. doi: 10.1038/ncomms14689

Figure 3. Loss of hepatic ACC activity has minimal impact on whole-body physiology in DEN-treated mice.

Figure 3

Liver (a) triglyceride and (b) cholesterol content, and (c) body weight and (d) adipose weight of DEN-treated LDKO and Flox mice at 40 weeks of age. (e) Blood glucose concentrations over time and (f) integrated area under the curve (AUC) during a glucose tolerance test in DEN-treated LDKO and Flox mice at 22 weeks of age. (g) Serum insulin levels in random-fed or 12 h-fasted Flox and LDKO mice at 22 weeks of age. For a–g, n=10 Flox and 11 LDKO mice. Statistical significance was analysed by two-tailed t-test (g was analysed by one-way analysis of variance followed by Tukey's post hoc analysis.) Data are represented as mean±s.e.m.