Table 1. Characteristics of gastric cancer harboring TNIK amplification.
Samples | Country | Sex | Age | TNIK FISH | TNIK IHC | Pathological type | TNM | β-Catenin IHC |
---|---|---|---|---|---|---|---|---|
GC-160 | China | M | 18 | AMP | 3+C | Diffused | T3N2M0 | CM++ |
GC-241 | China | M | 39 | AMP | 2+C | Diffused | T3N2M0 | CM++ |
GC-242 | China | M | 62 | AMP | 2∼3+C | Intestinal | T3N1M0 | CM++ |
GC-260 | China | F | 52 | AMP | 3+C | Diffused | T3N1M0 | CM+++ |
GC-268 | China | M | 69 | AMP | 3+C | Diffused | T3N1M0 | CM+++ |
GC-274 | China | M | 86 | AMP | 3+C | Diffused | T3N0M0 | C+ |
GC-278 | China | M | 50 | AMP | 3+C | Diffused | T3N1M0 | CMN+++ |
GC-288 | China | M | 64 | AMP | 2+C | Diffused | T3N2M0 | CM+++ |
Abbreviations: AMP, amplification; FISH, fluorescence in situ hybridization; IHC, immunohistochemistry; TNIK, Traf2- and Nck-interacting kinase; TNM, tumor node metastases.