Table 3. Genetic aberrations in gastric cancer with TNIK amplification.
GC-241 | GC-268 | GC-160 | GC-242 | GC-274 | GC-288 | |
---|---|---|---|---|---|---|
CTNNB1 | wt | wt | wt | wt | M662I | wt |
AXIN1 | wt | wt | wt | wt | wt | wt |
APC | wt | wt | wt | wt | p.R216* | wt |
PI3KCA | wt | wt | wt | wt | wt | wt |
Braf | wt | wt | wt | wt | wt | wt |
Kras | wt | wt | wt | wt | wt | wt |
ERBB2 | wt | AMP | wt | wt | wt | wt |
ERBB3 | wt | wt | wt | wt | wt | wt |
FGFR2 | wt | wt | wt | wt | wt | AMP |
Met | wt | wt | wt | wt | wt | wt |
Abbreviations: AMP, amplification; TNIK, Traf2- and Nck-interacting kinase; wt, wild type.