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. 2014 Apr 10;5(4):e1155. doi: 10.1038/cddis.2014.122

Table 2. Correlation between expression of FAP protein and clinicopathological characteristics in OSCC patients (n=84).

Variables FAP (%)
  n High expression Low expression P-value
Gender
 Male 54 24 (44.4%) 30 (55.6%)  
 Female 30 11 (36.7%) 19 (63.3%) 0.645
         
Age (years)
 ≥54 35 15 (42.9%) 20 (57.1%)  
 <54 49 17 (47.2%) 32 (52.8%) 0.813
         
Smoking
 Yes 38 18 (47.4%) 20 (52.6%)  
 No 46 16 (33.3%) 30 (66.7%) 0.267
         
Site
 Tongue 38 25 (65.8%) 13 (34.2%)  
 Buccal mucosa 24 16 (66.7%) 8 (33.3%)  
 Gingival 18 11 (61.1%) 7 (38.9%)  
 Other 4 3 (75%) 1 (25%) 0.955
         
Differentiation
 Well differentiated 32 20 (62.5%) 12 (37.5%)  
 Moderate to poorly differentiated 52 38 (70.4%) 16 (29.6%) 0.483
         
Alcohol
 Yes 29 17 (58.6%) 12 (41.4%)  
 No 55 39 (70.9%) 16 (29.1%) 0.331
         
Recurrence
 Yes 19 12 (63.2%) 7 (36.8%)  
 No 65 38 (58.5%) 27 (41.5%) 0.795
         
T classification
 T1+T2 48 21 (43.8%) 27 (56.2%)  
 T3+T4 26 19 (73.1%) 7 (26.9%) 0.027
         
N classification
 N0+N1 51 23 (45.1%) 28 (54.9%)  
 N2+N3 33 24 (72.7%) 9 (27.3%) 0.015
         
Distant metastasis
 M1 6 5 (83.3%) 1 (16.7%)  
 M0 78 38 (55.9%) 30 (44.1%) 0.391
         
Clinical stage
 I–II 50 18 (36.0%) 32 (64.0%)  
 III–IV 34 22 (64.7%) 12 (35.3%) 0.014

Bold values indicate statistical significance, P<0.05