Table 2. Correlation between expression of FAP protein and clinicopathological characteristics in OSCC patients (n=84).
| Variables | FAP (%) | |||
|---|---|---|---|---|
| n | High expression | Low expression | P-value | |
| Gender | ||||
| Male | 54 | 24 (44.4%) | 30 (55.6%) | |
| Female | 30 | 11 (36.7%) | 19 (63.3%) | 0.645 |
| Age (years) | ||||
| ≥54 | 35 | 15 (42.9%) | 20 (57.1%) | |
| <54 | 49 | 17 (47.2%) | 32 (52.8%) | 0.813 |
| Smoking | ||||
| Yes | 38 | 18 (47.4%) | 20 (52.6%) | |
| No | 46 | 16 (33.3%) | 30 (66.7%) | 0.267 |
| Site | ||||
| Tongue | 38 | 25 (65.8%) | 13 (34.2%) | |
| Buccal mucosa | 24 | 16 (66.7%) | 8 (33.3%) | |
| Gingival | 18 | 11 (61.1%) | 7 (38.9%) | |
| Other | 4 | 3 (75%) | 1 (25%) | 0.955 |
| Differentiation | ||||
| Well differentiated | 32 | 20 (62.5%) | 12 (37.5%) | |
| Moderate to poorly differentiated | 52 | 38 (70.4%) | 16 (29.6%) | 0.483 |
| Alcohol | ||||
| Yes | 29 | 17 (58.6%) | 12 (41.4%) | |
| No | 55 | 39 (70.9%) | 16 (29.1%) | 0.331 |
| Recurrence | ||||
| Yes | 19 | 12 (63.2%) | 7 (36.8%) | |
| No | 65 | 38 (58.5%) | 27 (41.5%) | 0.795 |
| T classification | ||||
| T1+T2 | 48 | 21 (43.8%) | 27 (56.2%) | |
| T3+T4 | 26 | 19 (73.1%) | 7 (26.9%) | 0.027 |
| N classification | ||||
| N0+N1 | 51 | 23 (45.1%) | 28 (54.9%) | |
| N2+N3 | 33 | 24 (72.7%) | 9 (27.3%) | 0.015 |
| Distant metastasis | ||||
| M1 | 6 | 5 (83.3%) | 1 (16.7%) | |
| M0 | 78 | 38 (55.9%) | 30 (44.1%) | 0.391 |
| Clinical stage | ||||
| I–II | 50 | 18 (36.0%) | 32 (64.0%) | |
| III–IV | 34 | 22 (64.7%) | 12 (35.3%) | 0.014 |
Bold values indicate statistical significance, P<0.05