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. 2014 Apr 10;5(4):e1166. doi: 10.1038/cddis.2014.133

Table 1. IC50 values for MPT0G009 or SAHA for different recombinant HDAC isoforms.

  IC50 (nM) of HDAC isoforms enzymea
Compound HDAC1 HDAC2 HDAC3 DHAC8 HDAC4 HDAC6
MPT0G009 4.62±0.81 5.16±0.76 1.91±0.22 22.48±2.16 >104 8.43±0.72
SAHA 45.97±5.62 96.90±8.43 33.87±2.38 542.83±32.73 >104 15.50±1.38
a

Data represent the mean±S.E.M. from three replicate experiments