Table 3. The MTD of MPT0G009.

Compound	Dose (mg/kg)	Schedule	Mouse no.	Change of body weight (%)			Lethality (%)
				Day 7	Day 14	Day 21
MPT0G009	250	p.o., qd × 7	6	+8.7±0.5	+17.0±0.4	+22.6±0.6	0
	500	p.o., qd × 7	6	+1.6±0.3	+16.5±0.6	+24.0±0.9	0
	1000	p.o., qd × 7	6	+4.4±0.6	+12.0±0.7	+15.3±0.8	0

Abbreviation: MTD, maximum tolerated dose

Data in the column of ‘change of body weight' represent mean±S.E.M.