Table 3.
Relative risk for adverse pregnancy outcomes in RA and SLE
RA* | SLE | |
---|---|---|
Hypertension/preelampsia | Possibly | 20 % |
Preterm delivery including PPROM | Odds ratio 1.5 compared to controls | 40 % |
C-section rate | Increased | Increased |
SGA | Yes | Yes |
Fetal/neonatal death | No | 17 % |
Anti-Ro/SSA, Anti-La/ SSB positive patients | ||
Neonatal lupus | 14–20 % | 14–20 % |
CCHB | 2 %, recurrence rate 17 % | 2 %, recurrence rate 17 % |
*RA patients are less commonly positive for anti-Ro/SS-A and anti-La/SS-B antibodies than are patients with SLE, but when antibody-positive these patients are subject to the same risk for neonatal lupus in their offspring