Table 2.
Sequence types (STs), allele profiles of 50 carbapenem-resistant A. baumannii isolates, carbapenem-hydrolyzing class D β-lactamase genes, minimum inhibitory concentration (MIC), site of isolation and patient outcome
| Sample ID | Site of isolation | Allele profile | ST | Carbapenem-hydrolyzing class D β-lactamase genes | MIC R ≥ 8 (mg/L) | Patient outcome | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| gltA | gyrB | gdhB | recA | cpn60 | gpi | rpoD | bla OXA-51 | bla OXA-23 | bla OXA-24 | bla OXA-58 | IMI | |||||
| A. baumannii | 21 | ETA | 1 | 3 | 3 | 2 | 2 | 96 | 3 | 195 | + | + | − | − | 25 | Deceased |
| A. baumannii | 22 | ETA | 1 | 3 | 3 | 2 | 2 | 96 | 3 | 195 | + | + | – | – | 20 | Deceased |
| A. baumannii | 30 | ETA | 1 | 3 | 3 | 2 | 2 | 97 | 3 | 208 | + | + | – | – | 25 | Deceased |
| A. baumannii | 33 | ETA | 1 | 3 | No gene | 2 | 2 | 97 | 3 | NA | + | + | – | – | 25 | Deceased |
| A. baumannii | 34 | ETA | 1 | 3 | 3 | 2 | 2 | 97 | 3 | 208 | + | – | – | – | 35 | Deceased |
| A. baumannii | 36 | ETA | 1 | 3 | 3 | 2 | 2 | 97 | 3 | 208 | + | + | – | – | 20 | Deceased |
| A. baumannii | 37 | ETA | 1 | 3 | 3 | 2 | 2 | 97 | 3 | 208 | + | + | – | – | 30 | Deceased |
| A. baumannii | 44 | Blood | 1 | 3 | 3 | 2 | 2 | 97 | 3 | 208 | + | + | – | – | 25 | Deceased |
| A. baumannii | 46 | Urine | 1 | 3 | 3 | 2 | 2 | 97 | 3 | 208 | + | + | – | – | 25 | Deceased |
| A. baumannii | 47 | Urine | 1 | 3 | No gene | 2 | 2 | 97 | 3 | NA | + | + | – | – | 30 | Discharged |
| A. baumannii | 49 | Urine | 1 | 3 | 3 | 2 | 2 | 96 | 3 | 195 | + | + | – | – | 25 | Deceased |
| A. baumannii | 5 | ETA | 1 | 12 | 3 | 2 | 2 | 79 | 3 | 1114 | + | + | – | – | 20 | Deceased |
| A. baumannii | 29 | ETA | 1 | 87 | 3 | 2 | 2 | 96 | 3 | 13929a | + | + | – | – | 20 | Discharged |
| A. baumannii | 24 | ETA | 1 | 107 | 12 | 10 | 23 | 195 | 26 | 723 | + | + | – | – | 25 | Deceased |
| A. baumannii | 25 | ETA | 1 | 107 | 12 | 10 | 23 | 195 | 26 | 723 | + | + | – | – | 25 | Deceased |
| A. baumannii | 38 | ETA | 1 | 107 | 12 | 10 | 23 | 195 | 26 | 723 | + | + | – | – | 30 | Deceased |
| A. baumannii | 48 | urine | 1 | 107 | 12 | 10 | 23 | 195 | 26 | 723 | + | + | – | – | 25 | Deceased |
| A. baumannii | 1 | ETA | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 30 | Deceased |
| A. baumannii | 3 | ETA | 10 | 12 | 4 | 11 | 4 | 79 | 5 | 945 | + | + | – | – | 15 | Deceased |
| A. baumannii | 4 | ETA | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 35 | Discharged |
| A. baumannii | 8 | ETA | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 35 | Deceased |
| A. baumannii | 11 | ETA | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 20 | Deceased |
| A. baumannii | 14 | ETA | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 20 | Deceased |
| A. baumannii | 16 | ETA | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 25 | Discharged |
| A. baumanii | 18 | ETA | 10 | 12 | No gene | 11 | 4 | 98 | 5 | NA | + | + | – | – | 20 | Deceased |
| A. baumanii | 19 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 20 | Deceased |
| A. baumannii | 20 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 20 | Deceased |
| A. baumannii | 23 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 15 | Deceased |
| A. baumannii | 26 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 25 | Deceased |
| A. baumannii | 27 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 20 | Deceased |
| A. baumannii | 28 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 20 | Deceased |
| A. baumannii | 31 | ETA | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 25 | Deceased |
| A. baumannii | 32 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 20 | Deceased |
| A. baumannii | 35 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 25 | Deceased |
| A. baumannii | 40 | ETA | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 25 | Deceased |
| A. baumannii | 41 | Blood | 10 | 12 | 4 | 11 | 4 | 100 | 5 | 441 | + | + | – | – | 25 | Discharged |
| A. baumannii | 45 | ETA | 10 | 12 | 4 | 11 | 4 | 98 | 5 | 231 | + | + | – | – | 20 | Deceased |
| A. baumannii | 12 | ETA | 12 | 17 | 12 | 1 | 29 | 102 | 39 | 236 | + | + | – | – | 35 | Deceased |
| A. baumannii | 17 | ETA | 12 | 17 | 12 | 1 | 29 | 102 | 39 | 236 | + | + | – | – | 35 | Deceased |
| A. baumannii | 2 | ETA | 24 | 92 | 96 | 11 | 49 | 162 | 26 | 499 | + | + | – | – | 20 | Discharged |
| A. baumannii | 6 | ETA | 24 | 92 | 96 | 11 | 49 | 162 | 26 | 499 | + | + | – | – | 25 | Deceased |
| A. baumannii | 7 | ETA | 24 | 92 | 96 | 11 | 49 | 162 | 26 | 499 | + | + | – | – | 20 | Deceased |
| A. baumannii | 13 | ETA | 24 | 92 | 96 | 11 | 49 | 162 | 26 | 499 | + | + | – | – | 15 | Deceased |
| A. baumannii | 15 | ETA | 24 | 92 | 96 | 11 | 49 | 162 | 26 | 499 | + | + | – | – | 15 | Deceased |
| A. baumannii | 39 | ETA | 24 | 92 | 96 | 11 | 49 | 162 | 26 | 499 | + | + | – | – | 35 | Deceased |
| A. baumannii | 42 | Blood | 24 | 92 | 96 | 11 | 49 | 162 | 26 | 499 | + | + | – | – | 25 | Deceased |
| A. baumannii | 50 | Swab | 24 | 92 | 96 | 11 | 49 | 162 | 26 | 499 | + | + | – | – | 20 | Deceased |
| A. baumannii | 43 | Blood | 28 | 38 | 45 | 1 | 16 | 66 | 2 | 1089 | + | – | – | – | 25 | Deceased |
| A. baumannii | 9 | ETA | 44 | 73 | No gene | 11 | 44 | ‡ | 4 | NA | + | + | – | – | 40 | Deceased |
| A. baumannii | 10 | ETA | 44 | 73 | No gene | 11 | 44 | ‡ | 4 | NA | + | + | – | – | 20 | Discharged |
ETA endotracheal aspirate, + positive, − negative
a New sequence type (ST13929)
‡ gpi 173, 1 difference found. 33T → 33C