Table 3.
Diagnostic performance of M2BPGi in 680 patients with chronic hepatitis C
| Fibrosis stage | Cutoff | AUC | Sensitivity | Specificity | P value | |
|---|---|---|---|---|---|---|
| ≥F2 | M2BPGi | 0.945 | 0.774 (0.736, 0.812) | 0.745 | 0.694 | Reference |
| APRI | 0.635 | 0.787 (0.750, 0.824) | 0.708 | 0.799 | >0.05 | |
| FIB4 | 3.145 | 0.702 (0.661, 0.743) | 0.650 | 0.686 | <0.001 | |
| GPR | 0.221 | 0.764 (0.726, 0.801) | 0.704 | 0.716 | >0.05 | |
| ≥F4 | M2BPGi | 1.355 | 0.892 (0.851, 0.933) | 0.868 | 0.786 | Reference |
| (Cirrhosis) | APRI | 0.885 | 0.873 (0.835, 0.910) | 0.838 | 0.783 | >0.05 |
| FIB4 | 4.395 | 0.818 (0.768, 0.868) | 0.750 | 0.775 | <0.05 | |
| GPR | 0.291 | 0.851 (0.808, 0.894) | 0.882 | 0.691 | >0.05 |