. 2015 Oct 15;1:15. doi: 10.1186/s40738-015-0008-z

Table 3.

Two dose methotrexate (MTX) for treatment of ectopic pregnancy

	Day 0	Day 4	Day 7	Day 11	Day 14
Labs	1. β-hCG	β-hCG	1. β-hCG	β-hCG	1. β-hCG
	2. Safety labs (complete blood count, BUN, creatinine, AST, ALT)		2. Safety labs		2. Safety labs
	3. Blood type and antibody screen		2. Safety labs		2. Safety labs
Action	Give MTX (50 mg/m2 of body surface area IM)	Give MTX (50 mg/m2 of body surface area IM)	β-hCG decline <15 % from Day 4 to Day 7: Give MTX	β-hCG decline <15 % from Day 7 to Day 11: Give MTX	β-hCG decline <15 % from Day 11 to Day 14: Refer for surgery
Action	Give MTX (50 mg/m2 of body surface area IM)	Give MTX (50 mg/m2 of body surface area IM)	β-hCG decline >15 % from Day 4 to Day 7: Check β-hCG at 1 week intervals until zero.	β-hCG decline >15 % from Day 7 to Day 11: Check β-hCG at 1 week intervals until zero.	β-hCG decline >15 % from Day 11 to Day 14: Check β-hCG at 1 week intervals until zero.