Table 4. Synthesis of N-Protected Aminocyclopropanes 6a–h from N-Vinylphthalimide (5).
Isolated yield for reaction on 10 mmol scale, 2.1 g isolated with 7:1 d.r. See the Supporting Information for details.
Relative configuration (both cis and trans) confirmed by X-ray diffraction.
Major isomer depicted.