Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Induction of type I IFNs by intracellular bacteria. Type I IFNs can be induced via cytosolic nucleic acid sensors RIG-I, MDA5, RNA Pol III, cGAS, and STING or nucleic acid-sensing TLR3, 7 or 9. Bacterial products like LPS and MDP can signal the production of type I IFNs via TLR4 or NOD2/RIP2, respectively.
