Table 1.
Demographic and baseline characteristics for completed subjects.
| Oxytocin (n = 11) | Placebo (n = 11) | |||
|---|---|---|---|---|
| n | % | n | % | |
| Male | 6 | 55 | 5 | 45 |
| Caucasian | 4 | 36 | 1 | 9 |
| African American | 5 | 45 | 7 | 64 |
| Hispanic | 0 | 0 | 2 | 18 |
| Other | 2 | 18 | 1 | 9 |
| Psychoactive Medications: | ||||
| SSRI | 2 | 18 | 1 | 9 |
| Trazodone | 1 | 9 | 1 | 9 |
| Mirtazapine | 0 | 0 | 1 | 9 |
| Misc. Prescribed Opioid | 1 | 9 | 3 | 27 |
| Mean | SD | Mean | SD | |
|---|---|---|---|---|
| Age (years) | 49.3 | 9.67 | 49.6 | 9.63 |
| Education (years) | 12.6 | 2.4 | 11.1 | 1.8 |
| Methadone (mg/day) | 105.5 | 27.7 | 97.3 | 23.6 |
| Heroin, 30-day* | 0.02 | 0.05 | 0.01 | 0.02 |
| Heroin, lifetime† | 0.27 | 0.17 | 0.31 | 0.16 |
| Cocaine, 30-day* | 0.81 | 0.28 | 0.92 | 0.19 |
| Cocaine, lifetime† | 0.25 | 0.17 | 0.49 | 0.23 |
| Baseline Measures | Mean | SD | Mean | SD |
|---|---|---|---|---|
| Cocaine Use, Self-Report ($) | 24.5 | 28.2 | 31.5 | 25.9 |
| Cocaine Use, BE (ng/mg) | 70.66 | 49.12 | 68.44 | 61.8 |
| Cocaine Craving | 0.49 | 0.22 | 0.46 | 0.23 |
| Cocaine Urge to Use | 0.48 | 0.24 | 0.50 | 0.20 |
| Heroin Craving | 0.11 | 0.17 | 0.08 | 0.08 |
| Heroin Urge to Use | 0.15 | 0.28 | 0.06 | 0.06 |
| IAT score | −0.16 | 0.46 | −0.28 | 0.23 |
*
number of days of drug use/past 30 days
†
number of years using at least three times per week/patient's age.
SSRI = selective serotonin reuptake inhibitor, SD = standard deviation, BE = benzoylecgonine.