Table 12.

P values testing Hardy–Weinberg proportion and test for heterogeneity of studies included in the meta-analysis for TaqITt polymorphism respectively.

Study	Intervention	Controls	Odds ratio	95% CI	z	P
Chang 2000	15/157	14/248	1.766	0.828–3.766
Balazs Gyorffy 2002	28/107	33/103	0.752	0.414–1.367
Vaselin Scrabic 2003	55/134	72/132	0.580	0.357–0.943
J J San Pedro 2005	36/71	43/88	1.076	0.576–2.012
Diego Garcia 2007	79/216	69/203	1.120	0.750–1.673
C Panierakis 2009	64/100	59/96	1.115	0.625–1.990
Greear R M 2013	26/55	24/50	0.971	0.451–2.091
Chung Cheon 2015	15/81	8/113	2.983	1.199–7.423
Total (fixed effects)	318/921	322/1033	1.017	0.829–1.248	0.165	0.869
Total (random effects)	318/921	322/1033	1.062	0.785–1.438	0.390	0.697
Q	13.8658
DF	7
Significance level	P = 0.0536
I2 (inconsistency)	49.52%
95% CI for I2	0.00–77.47

Bias indicators: Begg–Mazumdar: Kendall’s Tau = 0.047619 P  > 0.9999 (low power); Egger: bias = 1.307065 (95% CI = −4.196619 to 6.810748) P = 0.5682; Harbord–Egger: bias = 1.410342 (92.5% CI = −3.284733 to 6.105417) P = 0.5305.

DF, degree of freedom; Q, heterogeneity in meta analysis.