Table 6.

P values testing Hardy–Weinberg proportion and test for heterogeneity of studies included in the meta-analysis for BsmI Bb polymorphism, respectively.

Study	Intervention	Controls	Odds ratio	95% CI	z	P
Chang 2000	16/157	16/248	1.645	0.798–3.393
Balazs Gyorffy 2002	53/107	44/103	1.316	0.764–2.268
Vaselin Scrabic 2003	58/134	74/132	0.598	0.368–0.971
J J San Pedro 2005	40/71	44/88	1.290	0.688–2.418
Diego Garcia 2007	110/216	74/203	1.809	1.224–2.674
C Panierakis 2009	43/100	23/96	2.394	1.296–4.422
Chung Cheon 2015	13/81	4/113	5.210	1.632–16.633
Total (fixed effects)	333/866	279/983	1.430	1.160–1.762	3.347	0.001
Total (random effects)	333/866	279/983	1.534	1.001–2.350	1.966	0.049
Q	21.6238
DF	6
Significance level	P = 0.0014
I2 (inconsistency)	72.25%
95% CI for I2	40.02–87.16

Bias indicators: Begg–Mazumdar: Kendall’s Tau = −0.333333 P = 0.3813 (low power); Egger: bias = 2.518064 (95% CI = −4.133965 to 9.170093) P = 0.3752; Harbord–Egger: bias = 2.595692 (92.5% CI = −3.668787 to 8.860172) P = 0.3955.

DF, degree of freedom; Q, heterogeneity in meta analysis.