Table 8.

P values testing Hardy–Weinberg proportion and test for heterogeneity of studies included in the meta-analysis for FokI FF polymorphism respectively.

Study	Intervention	Controls	Odds ratio	95% CI	z	P
Balazs Gyorffy 2002	36/107	29/103	1.294	0.719–2.328
Tatijana Semunik 2005	42/132	73/232	1.016	0.642–1.609
J J San Pedro 2005	31/71	41/88	0.888	0.474–1.666
C Panierakis 2009	64/100	50/96	1.636	0.923–2.898
Greear R M 2013	21/55	28/50	0.485	0.223–1.058
Total (fixed effects)	194/465	221/569	1.057	0.817–1.367	0.420	0.675
Total (random effects)	194/465	221/569	1.036	0.733–1.465	0.202	0.840
Q	6.8448
DF	4
Significance level	P = 0.1443
I2 (inconsistency)	41.56%
95% CI for I2	0.00–78.48

Bias indicators: Begg–Mazumdar: Kendall’s Tau = −0.6 P = 0.00833 (low power); Egger: bias = −3.653382 (95% CI = −14.60785 to 7.301086) P = 0.3664; Harbord–Egger: bias = −3.796013 (92.5% CI = −13.262673 to 5.670648) P = 0.3612.

DF, degree of freedom; Q, heterogeneity in meta analysis.