Table 9.

P values testing Hardy–Weinberg proportion and test for heterogeneity of studies included in the meta-analysis for FokI Ff polymorphism respectively.

Study	Intervention	Controls	Odds ratio	95% CI	z	P
Balazs Gyorffy 2002	49/107	56/103	0.709	0.412–1.221
Tatijana Semunik 2005	63/132	136/232	0.645	0.419–0.991
J J San Pedro 2005	35/71	39/88	1.222	0.652–2.287
C Panierakis 2009	31/100	43/96	0.554	0.309–0.993
Greear R M 2013	21/55	22/50	0.786	0.361–1.714
Total (fixed effects)	199/465	296/569	0.724	0.564–0.929	−2.538	0.011
Total (random effects)	199/465	296/569	0.723	0.563–0.929	−2.535	0.011
Q	3.8098
DF	4
Significance level	P = 0.4324
I2 (inconsistency)	0.00%
95% CI for I2	0.00–79.45

Bias indicators: Begg–Mazumdar: Kendall’s Tau = −0.4 P = 0.4833 (low power); Egger: bias = 1.95378 (95% CI = 5.613844–9.521404) P = 0.4715; Harbord–Egger: bias = 2.01803 (92.5% CI = −4.313428 to 8.349488) P = 0.4557.

DF, degree of freedom; Q, heterogeneity in meta analysis.