Table 1.
List of the top genes up-regulated by [Ca2+]o treatment: Top 10 for each time point. p value assed based on pair-wise comparisons with the untreated controls using Student's t-test (two sided, unpaired, assuming unequal variances).
| Name | Symbol | Fold change | p-Value |
|---|---|---|---|
| Increased after 1 h | |||
| Chemokine (C-X-C motif) ligand 2 | CXCL2 | 1.335 | 0.0002 |
| Jun oncogene | JUN | 1.329 | 0.0080 |
| Chemokine (C-X-C motif) ligand 3 | CXCL3 | 1.323 | 0.0062 |
| RAB27B, member RAS oncogene family | RAB27B | 1.290 | 0.0057 |
| Nuclear receptor coactivator 7 | NCOA7 | 1.233 | 0.0064 |
| EPH receptor A2 | EPHA2 | 1.223 | 0.0264 |
| Increased after 4 h | |||
| Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | ID1 | 1.398 | 0.0374 |
| Growth arrest-specific 5 | GAS5 | 1.388 | 0.0015 |
| Cadherin 7, type 2 | CDH7 | 1.348 | 0.0095 |
| v-myc myelocytomatosis viral oncogene homolog (avian) | MYC | 1.266 | 0.0103 |
| WD repeat domain 43 | WDR43 | 1.263 | 0.0012 |
| Cyclin Y-like 1 | CCNYL1 | 1.260 | 0.0123 |
| Partner of NOB1 homolog (S. cerevisiae) | PNO1 | 1.241 | 0.0029 |
| BRCA2 and CDKN1A interacting protein | BCCIP | 1.241 | 0.0083 |
| SLIT-ROBO Rho GTPase activating protein 1 | SRGAP1 | 1.238 | 0.0006 |
| Phospholipase D1, phosphatidylcholine-specific | PLD1 | 1.230 | 0.0000 |
| Increased after 24 h | |||
| Sucrase-isomaltase (alpha-glucosidase) | SI | 5.320 | 1.17E−05 |
| RAB27B, member RAS oncogene family | RAB27B | 3.581 | 7.43E−03 |
| Klotho beta | KLB | 3.297 | 1.95E−03 |
| Regenerating islet-derived family, member 4 | REG4 | 3.211 | 6.46E−04 |
| Monoamine oxidase A | MAOA | 3.001 | 2.03E−03 |
| Potassium inwardly-rectifying channel, subfamily J, member 16 | KCNJ16 | 2.641 | 5.11E−06 |
| Aldo-keto reductase family 1, member D1 | AKR1D1 | 2.617 | 1.31E−04 |
| Similar to calpain 8 | LOC388743 | 2.479 | 1.63E−03 |
| Fibrinogen beta chain | FGB | 2.412 | 1.12E−03 |
| Lectin, galactoside-binding, soluble, 7 (galectin 7) | LGALS7 | 2.366 | 6.14E−03 |