Table 1. SNPs significantly associated with the polydactyly phenotype.
chr | position | A1/A2 | OR | mlm P a | logistic P b | nearest gene | distance c |
---|---|---|---|---|---|---|---|
2 | 6306869 | T/C | 76.25 | 3.44E-11 | 9.97E-08 | PRKAG2 | 0 |
2 | 7097528 | A/G | 0.03146 | 9.89E-10 | 1.29E-07 | ACTR3B | 282867 |
2 | 7978373 | C/T | 52.9 | 4.30E-10 | 3.48E-07 | RBM33 | 0 |
2 | 8003962 | C/T | 55.69 | 3.83E-12 | 8.20E-10 | RBM33 | 0 |
2 | 8263544 | A/G | 35.46 | 1.46E-10 | 1.86E-09 | RNF32 | 150902 |
2 | 8645181 | C/A | 37.82 | 3.09E-11 | 3.31E-09 | DNAJB6 | 14950 |
2 | 8678907 | C/A | 74.67 | 3.88E-11 | 1.32E-07 | DNAJB6 | 0 |
2 | 8909242 | G/C | 40.56 | 2.27E-10 | 3.41E-08 | PTPRN2 | 0 |
2 | 8909250 | C/T | 40.56 | 2.27E-10 | 3.41E-08 | PTPRN2 | 0 |
2 | 9251806 | T/C | 23.14 | 8.59E-10 | 3.78E-09 | PTPRN2 | 0 |
2 | 10070358 | G/A | 31.95 | 2.01E-10 | 1.20E-08 | DIP2C | 70587 |
2 | 10472227 | C/A | 30.86 | 2.64E-10 | 9.68E-09 | ADARB2 | 0 |
2 | 13408892 | A/T | 41.71 | 4.03E-12 | 1.83E-10 | PARD3 | 0 |
2 | 13408966 | A/G | 41.71 | 4.03E-12 | 1.83E-10 | PARD3 | 0 |
2 | 14923383 | G/A | 22.44 | 8.93E-10 | 4.47E-08 | MTPAP | 0 |
a mlm P stands for P value calculated by mixed linear model.
b logistic P stands for P value calculated by logistic model.
c distance column shows the distance between the significant SNPs and their nearest genes, either 3’ or 5’ flank.