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. Author manuscript; available in PMC: 2017 May 10.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2015 Sep 4;65:78–84. doi: 10.1016/j.pnpbp.2015.08.017

Figure 2.

Figure 2

Mean (+ SEM) percent time spent freezing during different drug and cue conditions 15 min after injection during conditioning on days 1 through 5. Systemic administration of the 5-HT2C receptor antagonist SB 242084 (0.25 or 1.0 mg/kg) reduced freezing to some cues during conditioning and facilitated discrimination. Overhead brackets indicate significant hypothesis driven comparisons (see main text). With regard to discrimination, on the 1.0 mg/kg SB 242084 group spent less time freezing to the CS− than the CS+ indicating discrimination. *p < 0.05, **p < 0.01, ***p < 0.001