Table 3. Association between inflammation-based parameters and clinicopathological factors in patients with breast cancer.
Variables | CRP | LMR | NLR | PLR | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
L | H | P | L | H | P | L | H | P | L | H | P | |
Age (y) | ||||||||||||
<50 | 59 | 2 | 0.08 | 8 | 53 | 0.69 | 31 | 30 | 0.67 | 39 | 22 | 0.15 |
≥50 | 209 | 26 | 38 | 197 | 128 | 107 | 173 | 62 | ||||
TS | ||||||||||||
<20 | 134 | 9 | 0.08 | 21 | 122 | 0.75 | 86 | 57 | 0.04 | 107 | 36 | 0.25 |
≥20 | 134 | 5 | 25 | 128 | 73 | 80 | 105 | 48 | ||||
ER | ||||||||||||
(–) | 38 | 5 | 0.58 | 5 | 48 | 0.65 | 25 | 18 | 0.62 | 37 | 6 | 0.03 |
(+) | 230 | 23 | 41 | 212 | 134 | 119 | 175 | 78 | ||||
PgR | ||||||||||||
(–) | 68 | 6 | 0.82 | 9 | 65 | 0.46 | 38 | 36 | 0.69 | 51 | 23 | 0.55 |
(+) | 200 | 22 | 37 | 185 | 121 | 101 | 161 | 61 | ||||
HER2 | ||||||||||||
(–) | 222 | 25 | 0.59 | 38 | 209 | 0.83 | 135 | 112 | 0.53 | 181 | 66 | 0.17 |
(+) | 46 | 3 | 8 | 41 | 24 | 25 | 31 | 18 | ||||
LN | ||||||||||||
(–) | 191 | 18 | 0.51 | 32 | 177 | 0.86 | 120 | 89 | 0.06 | 158 | 51 | 0.02 |
(+) | 77 | 10 | 14 | 73 | 39 | 48 | 54 | 33 | ||||
NG | ||||||||||||
1–2 | 183 | 12 | 1 | 30 | 172 | 0.61 | 111 | 91 | 0.45 | 143 | 59 | 0.68 |
3 | 83 | 9 | 16 | 76 | 46 | 46 | 68 | 24 |
Abbreviations: CRP, C-reactive protein; LMR, lymphocyte-to-monocyte ratio; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; TS, tumor size; L, low inflammation-based parameter group; H, high inflammation-based parameter group; P, P-value; ER, estrogen receptor; PgR, progesterone receptor; HER2, human epidermal growth factor receptor 2; LN, lymph node involvement; NG, nuclear grade.