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. 2017 May 10;12(5):e0177137. doi: 10.1371/journal.pone.0177137

Table 3. Association between inflammation-based parameters and clinicopathological factors in patients with breast cancer.

Variables CRP LMR NLR PLR
L H P L H P L H P L H P
Age (y)
    <50 59 2 0.08 8 53 0.69 31 30 0.67 39 22 0.15
    ≥50 209 26 38 197 128 107 173 62
TS
    <20 134 9 0.08 21 122 0.75 86 57 0.04 107 36 0.25
    ≥20 134 5 25 128 73 80 105 48
ER
     (–) 38 5 0.58 5 48 0.65 25 18 0.62 37 6 0.03
    (+) 230 23 41 212 134 119 175 78
PgR
    (–) 68 6 0.82 9 65 0.46 38 36 0.69 51 23 0.55
     (+) 200 22 37 185 121 101 161 61
HER2
     (–) 222 25 0.59 38 209 0.83 135 112 0.53 181 66 0.17
     (+) 46 3 8 41 24 25 31 18
LN
     (–) 191 18 0.51 32 177 0.86 120 89 0.06 158 51 0.02
     (+) 77 10 14 73 39 48 54 33
NG
    1–2 183 12 1 30 172 0.61 111 91 0.45 143 59 0.68
    3 83 9 16 76 46 46 68 24

Abbreviations: CRP, C-reactive protein; LMR, lymphocyte-to-monocyte ratio; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; TS, tumor size; L, low inflammation-based parameter group; H, high inflammation-based parameter group; P, P-value; ER, estrogen receptor; PgR, progesterone receptor; HER2, human epidermal growth factor receptor 2; LN, lymph node involvement; NG, nuclear grade.