. 2017 May 10;12(5):e0177447. doi: 10.1371/journal.pone.0177447

Table 1. Obesity and glucose tolerance in ND- and HFD-fed mice.

	Body Weight gain (g)	OGTT (mg/dL)				iAUC (mg/dL × min)
	Body Weight gain (g)	0	30	60	120 (min)	iAUC (mg/dL × min)
2W ND	4.7±0.3	33.9±2.6	243.9±24.5	256.2±21.4	122.7±9.7	316.1±29.0
2W HFD	12.2±0.9^***	48.4±2.3^***	239.2±15.4	334.8±18.7^*	189.7±19.5^**	380.9±26.8
8W ND	30.5±1.1	48.0±3.2	155.4±11.5	132.1±8.3	78.2±3.9	131.9±11.6
8W HFD	46.2±1.3^***	88.4±7.6^***	249.3±21.8^**	349.9±28.3^***	214.9±20.0^***	339.8±36.8^***

Mice were fed a normal diet (ND) or high-fat diet (HFD) for two (2W) or eight (8W) weeks. Obesity and glucose tolerance are indicated by body weight, fasting blood glucose, oral glucose tolerance test (OGTT), and area under the OGTT curve (iAUC). Fasting blood glucose is indicated by the 0 min sample of the OGTT.

* p<0.05,

** p<0.01,

*** p<0.001 vs. mice fed ND for2W or 8W (n = 9–10).