Table 2. Clinical-psychopathological features of subjects included in the study.
| (1) Controls | (2) De novo CD patients | (3) CD patients on GFD | Kruskal-Wallis ANOVA | Mann-Whitney test p = | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Median | IQ range | Median | IQ range | Median | IQ range | H(2,60) | p = | 1 vs. 2 | 1 vs. 3 | 2 vs. 3 | |
| Age, years | 29.50 | 26.00‒42.00 | 33.00 | 24.00-45.00 | 35.50 | 29.50-39.00 | 0.601 | 0.740 | - | - | - |
| Education, years | 14.00 | 13.50-16.00 | 13.00 | 13.00-13.00 | 15.50 | 13.00-18.00 | 3.380 | 0.501 | - | - | - |
| MMSE | 30.00 | 29.00-30.00 | 30.00 | 29.00-30.00 | 30.00 | 30.00-30.00 | 3.155 | 0.520 | - | - | - |
| HDRS | 2.00 | 0.00-4.00 | 7.00 | 2.00-9.00 | 2.00 | 0.50-5.00 | 9.272 | 0.01 | 0.006 | 0.849 | 0.015 |
| NPI | 0.00 | 0.00-1.00 | 4.50 | 2.00-12.00 | 0.50 | 0.00-2.00 | 19.338 | 0.0001 | 0.00012 | 0.379 | 0.0009 |
| Chi-square | p = | ||||||||||
| Sex, males/females | 8/12 | 4/16 | 6/14 | 1.90 | 0.386 | ||||||
| Co-morbidity, yes/no | 0/20 | 9/11 | 8/12 | 12.0 | 0.002 | ||||||
| SCID-I, yes/no | 0/20 | 5/15 | 0/20 | 10.9 | 0.004 | ||||||
CD = celiac disease; GFD = gluten-free diet; IQ = interquartile range; MMSE = Mini Mental State Examination; HDRS = 17 item-Hamilton Depression Rating Scale; NPI = neuropsychiatric inventory; SCID-I = Structured Clinical Interview for DSM-IV Axis I; NS = not significant; bold numbers = statistically significant p values.