Figure 6.
Model predictions for the relationship between FA length and assembled FN fibril morphometrical and mechanical properties. (Left three panels) (A) Substrate force, (B) relaxed FN fibril length, (C) stretched FN fibril length, and (D) fibril extensibility (stretched-relaxed FN length ratio) are plotted as a function of predicted FA length, for different values of substrate stiffness ksub. Each dot represents a single simulation. (Right panels) (A) FA stress (substrate force-FA length ratio), (B) relaxed FN length-FA length ratio, (C) stretched FN length-FA length ratio, and (D) FN extensibility-FA length ratio, as determined by a linear least squares fit, are shown as a function of ksub. To see this figure in color, go online.