Figure 5.

Brownian dynamics simulations of active actin networks in 3D. Networks with actin nucleation rates of (a) 0.1 and (b) 0.01 μM⁻¹ s⁻¹. All simulated networks have 25 M actin, 1% ACPs to actin, and 1% myosin II motors to actin in a 3 × 3 × 3 μm³ domain with periodic boundary conditions. The actin turnover (treadmilling) rate is set to 300 s⁻¹, which is sufficient to maintain homogeneous rather than clustered networks in these simulations. Orange represents motors, yellow represents ACPs, and fibers represent actin filaments. The color scale applies to the actin filaments and represents a tensile force range from 0 (blue) to 100 pN (red).