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. 2017 May 11;8:256. doi: 10.3389/fphar.2017.00256

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Copyright © 2017 Yu, Liu, Yuan, Li, Yang, Yuan, Sun, Zhang and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SRT1720 altered gene expressions of Nrf2/ARE signalling in ANTI-induced liver hepatotoxicity and cholestasis in mice. (A) Nrf2, (B) SOD, (C) GCLm, (D) GCLc, (E) Nqo1, and (F) HOO-1. Data are the mean ± SD (n = 6). ^∗P < 0.05 versus vehicle; ^#P < 0.05 versus vehicle +ANIT.