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. 2017 Apr 6;8(5):1379–1391. doi: 10.1016/j.stemcr.2017.03.007

Figure 3.

Figure 3

Reduced Tumor Marker Expression in Reprogrammed Melanoma Cells

(A) Histological staining for the melanoma marker S100B in melanomas derived from HT-144, Mewo, and SKMEL147 cells and their respective reprogrammed progeny.

(B) In contrast to melanomas, S100B expression is restricted to neuronal-like cells in HT-144-iPCC-derived teratomas (indicated by arrows).

(C) Histological staining for epithelial cytokeratins (PanCK) in HT-144-iPCC-derived tumors and melanomas derived from the parental HT-144 cells.

(D) Histological analysis of the expression of the proliferation marker KI67 in melanomas derived from HT-144, Mewo, and SKMEL147 cells and their respective reprogrammed progeny.