Fig. 7.

Schematic showing proposed antagonistic actions of M2A and M2B in a neuronal growth cone during development (a) and within a neuromuscular junction (NMJ) at maturity (b). M2A retraction is indicated by blue arrows; M2B outgrowth is indicated by magenta arrows. P defines the peripheral zone of growth cone, separated from C, the central zone, by a dotted line. The NMJ is stylised for simplicity: neural input depicted by the same growth cone cartoon; muscle end-plate and fibre indicated in pink