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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: HLA. 2016 Dec 15;89(1):39–46. doi: 10.1111/tan.12942

Table 5.

Mismatches between donor and recipient observed in the ARD-encoding exons

Mismatch in Pair No. Observed Location of Variation
Exon/Codon AA Substitution/Location in Protein
Comments
A*03:01:02 vs A*03:01:01:01 1 Exon 3/156 synonymous Confirmed by Sanger; GenBank: KX686515 (*03:01:02)
A*68:01:02:01 vs A*68:01:01:02
A*68:01:02:02 vs A*68:01:01:02
A*68:01:02:02var vs A*68:01:01:02
3 Exon 2/10 synonymous Var: intron variation in allele
B*35:12:01 vs B*35:03:01 1 Exon 3/V99L, N114D, Y116F/α2 9/10 match mistakenly in sample set; prior typing consistent with NGS
C*03:04:53 vs C*03:04:01 1 Exon 2/2 synonymous Confirmed by Sanger; GenBank: KX686518
C*04:01:10 vs C*04:01:01:06 1 Exon 2/42 synonymous Confirmed by Sanger
DQA1*01:14 vs DQA1*01:03:01 1 Exon 2/F15L/α1 Not typed previously; confirmed by Sanger; GenBank:KX686517
DQB1*06:79:01 vs. DQB1*06:02:01 1 Exon 2/V38A/β1 Missed in prior typing; confirmed by Sanger; GenBank: KX686513 (*06:79)